The diagnostic value of platelet distribution width in patients with mild COVID-19

• Main Authors: Fan, Z. (Author), Wang, S. (Author), Wang, Y. (Author), Zhuang, C. (Author)
• Format: Article
• Language: English
• Published: John Wiley and Sons Inc 2021
• Subjects: adult; Adult; aged; Aged; Article; blood; clinical article; coronavirus disease 2019; COVID-19; COVID-19 Testing; diagnosis; diagnostic value; disease severity; epidemiology; female; Female; hospital admission; hospital discharge; human; Humans; male; Male; mean platelet volume; Mean Platelet Volume; middle aged; Middle Aged; mild disease; PDW; platelet distribution width; procedures; receiver operating characteristic; Retrospective Studies; retrospective study; risk factor; ROC Curve; sensitivity and specificity
• Online Access: View Fulltext in Publisher

 COVID-19 has a worldwide distribution; however, there is no effective diagnosis marker, especially for the mild-type COVID-19. The purpose of the current study was to identify parameters for mild-type COVID-19. We retrospectively analyzed a single-center data of patients with mild COVID-19. Forty patients diagnosed with COVID-19 were enrolled. Peripheral blood indices between the admission and discharge times were collected and analyzed. The platelet distribution width (PDW) was shown to be an indicator of significant change. The receiver operating characteristic curve for PDW was 0.7; the sensitivity and specificity for PDW were 82.5% and 55.0%, respectively. Therefore, a potential diagnostic value of PDW for mild-type COVID-19 was demonstrated. © 2021 The Authors. Journal of Clinical Laboratory Analysis published by Wiley Periodicals LLC