Serum osteoprotegerin level in hemodialysis patients using low-flux reused dialyzer in relation to atherosclerosis
Aims: To assess the relation of high serum OPG level and carotid atherosclerosis in maintenance hemodialysis (MHD) patients using low-flux reused dialyzer. Materials and Methods: We examined 209 MHD patients with and without carotid atherosclerosis (83 patients and 126 patients) to establish the rel...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
John Wiley and Sons Inc
2021
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Subjects: | |
Online Access: | View Fulltext in Publisher |
Summary: | Aims: To assess the relation of high serum OPG level and carotid atherosclerosis in maintenance hemodialysis (MHD) patients using low-flux reused dialyzer. Materials and Methods: We examined 209 MHD patients with and without carotid atherosclerosis (83 patients and 126 patients) to establish the relation between OPG and atherosclerosis. Results: The proportion of carotid atherosclerosis was 39.7%. The median serum OPG level was 45.3 pmol/L. Serum OPG had a good predicting value for atherosclerosis in MHD patients using low-flux reused dialyzer (AUC = 0.934, p < 0.001, cutoff value = 43.35 pmol/L, Se = 81.3%, Sp = 90.9%). Conclusions: In this study, serum OPG had a good predicting value for atherosclerosis in MHD patients using low-flux reused dialyzer. © 2021 The Authors. Journal of Clinical Laboratory Analysis published by Wiley Periodicals LLC. |
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ISBN: | 08878013 (ISSN) |
DOI: | 10.1002/jcla.23886 |