A computational model of glioma reveals opposing, stiffness-sensitive effects of leaky vasculature and tumor growth on tissue mechanical stress and porosity
A biphasic computational model of a growing, vascularized glioma within brain tissue was developed to account for unique features of gliomas, including soft surrounding brain tissue, their low stiffness relative to brain tissue, and a lack of draining lymphatics. This model is the first to couple no...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media Deutschland GmbH
2021
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Subjects: | |
Online Access: | View Fulltext in Publisher |