Synthesis, characterization and cytotoxic activity of S- benzyldithiocarbazate Schiff bases derived from 5-fluoroisatin, 5-chloroisatin, 5-bromoisatin and their crystal structures

Synthesis, characterization and cytotoxic activity of S- benzyldithiocarbazate Schiff bases derived from 5-fluoroisatin, 5-chloroisatin, 5-bromoisatin and their crystal structures

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Schiff bases were prepared from S-benzyldithiocarbazate with 5-fluro-, 5-chloro- and 5-bromoisatin. All are potential tridentate nitrogen, oxygen, sulfur donors. They were found to be selectively active against MCF-7 cell line (Human non-metastatic mammary gland adenocarcinoma cell line). The bromid...

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Bibliographic Details
Main Authors: Crouse, K.A (Author), How, F.N.-F (Author), Manan, M.A.F.A (Author), Rosli, R. (Author), Slawin, A.M.Z (Author), Tahir, M.I.M (Author), Watkin, D.J (Author)
Format: Article
Language:English
Subjects:
Dithiocarbazate
Isatin
MCF-7
Schiff base
Structure
Online Access:View Fulltext in Publisher
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