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01576nam a2200241Ia 4500 |
| 001 |
10.1016-j.clinre.2022.101948 |
| 008 |
220718s2022 CNT 000 0 und d |
| 020 |
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|a 22107401 (ISSN)
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| 245 |
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|a Hepatitis E infection with a benign course during vedolizumab treatment for Crohn's disease: A case report: Hepatitis E during vedolizumab therapy in IBD
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| 260 |
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|b Elsevier Masson s.r.l.
|c 2022
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| 856 |
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|z View Fulltext in Publisher
|u https://doi.org/10.1016/j.clinre.2022.101948
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|a We present a 49 year old female patient with Crohn's disease (CD) in remission on vedolizumab therapy who experienced a symptomatic, though benign, course of acute hepatitis E. Routine blood tests showed substantial elevation of liver enzymes and polymerase chain reaction (PCR) testing confirmed hepatitis E virus (HEV) infection. Vedolizumab therapy was paused, liver enzymes improved three weeks after infection and normalized after six months. The patient recovered completely from mild symptoms. This case shows that hepatitis E is a potential cause of acute hepatitis during vedolizumab therapy, and in this case the infection has run a benign course. © 2022 The Author(s)
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|a Crohn's disease
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|a Hepatitis E
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|a IBD
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| 650 |
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|a Vedolizumab
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| 700 |
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|a de Man, R.A.
|e author
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|a de Vries, A.C.
|e author
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|a Goetgebuer, R.L.
|e author
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|a Masclee, G.M.C.
|e author
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|a van der Eijk, A.A.
|e author
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|a van der Woude, C.J.
|e author
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| 773 |
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|t Clinics and Research in Hepatology and Gastroenterology
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