Prediction of overall yield of Gynura procumbens from ethanol-water + supercritical CO2 extraction using artificial neural network model

Gynura procumbens, also known as Sambung nyawa by Malays, is a traditional herb that can be found in Malaysian forests. Traditional Malays rely on this plant in many ways. The leaves can be eaten raw as a salad, and it is believed to have medicinal effects for humans suffering from cancer, diabetes,...

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Bibliographic Details
Main Authors: Abd Rahman, N. (Author), Idris, S.A (Author), Markom, M. (Author), Mohd Ali, J. (Author)
Format: Article
Language:English
Published: Elsevier Ltd 2022
Series:Case Studies in Chemical and Environmental Engineering
Subjects:
Online Access:View Fulltext in Publisher
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LEADER 02460nam a2200253Ia 4500
001 10.1016-j.cscee.2021.100175
008 220124s2022 CNT 000 0 und d
020 |a 26660164 (ISSN) 
245 1 0 |a Prediction of overall yield of Gynura procumbens from ethanol-water + supercritical CO2 extraction using artificial neural network model 
260 0 |b Elsevier Ltd  |c 2022 
490 1 |a Case Studies in Chemical and Environmental Engineering 
650 0 4 |a Co-solvent 
650 0 4 |a Extraction 
650 0 4 |a Herbs 
650 0 4 |a Separation 
650 0 4 |a Supercritical fluid 
856 |z View Fulltext in Publisher  |u https://doi.org/10.1016/j.cscee.2021.100175 
856 |z View in Scopus  |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-85122365574&doi=10.1016%2fj.cscee.2021.100175&partnerID=40&md5=9d2ce714c4bdf54916001311f28888b2 
520 3 |a Gynura procumbens, also known as Sambung nyawa by Malays, is a traditional herb that can be found in Malaysian forests. Traditional Malays rely on this plant in many ways. The leaves can be eaten raw as a salad, and it is believed to have medicinal effects for humans suffering from cancer, diabetes, and other afflictions. The extraction of G. procumbens has been conducted using various techniques, including supercritical fluid extraction (SFE). The study presents the methodology for an artificial neural network (ANN) model with the intention of predicting the overall yield, YT of G. procumbens in supercritical fluid depending on the SFE parameter, namely, water content in ethanol (10–30% v/v), temperature (60–70 °C), and pressure (18–24 MPa). The overall yield from SFE was optimal with a 15.90% wt/wt sample at 30% water content in ethanol, 70 °C and 24 MPa. A three-layer ANN model was generated using the experimental data obtained. The Levenberg–Marquardt back-propagation (LMP) algorithm with a trainlm transfer function was used to predict the YT. A total of 1–8 neurons in the hidden layer were trained, and the most suitable network found was with 6 neurons in the hidden layer. The value of the mean square error (MSE) was 0.3011, and the coefficient of determination (R2) was 0.9877, showing that the (3-6-1) model is a better option for predicting the YT. © 2021 The Authors 
700 1 0 |a Abd Rahman, N.  |e author 
700 1 0 |a Idris, S.A.  |e author 
700 1 0 |a Markom, M.  |e author 
700 1 0 |a Mohd Ali, J.  |e author 
773 |t Case Studies in Chemical and Environmental Engineering