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10.1016-j.oraloncology.2018.03.019 |
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220706s2018 CNT 000 0 und d |
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|a 13688375 (ISSN)
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|a Risk factors for salivary gland cancers in France: Results from a case-control study, the ICARE study
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|b Elsevier Ltd
|c 2018
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|z View Fulltext in Publisher
|u https://doi.org/10.1016/j.oraloncology.2018.03.019
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|a Objectives: Epidemiological studies on the risk factors for salivary gland cancers (SGC) are rare, concern a small sample size, and show inconsistent results. The aim of the present work was to analyze several risk factors for SGC, using the data from the ICARE study, a multicenter, population-based case-control study. Materials and methods: Data from 73 SGC cases and 3555 controls were collected using a standardized questionnaire on lifestyle habits, personal and family medical history, and lifetime occupational history. Odds ratios (OR) and 95% confidence intervals (CI) were estimated using unconditional logistic regressions. Results: Tobacco use and alcohol consumption were not associated with the risk of SGC. A history of head and neck cancer or that of cervicofacial radiotherapy was associated with a higher risk of SGC (OR = 17.06, 95% CI: 4.34–67.05, and OR = 31.74, 2.48–405.25, respectively). Significantly increased risks were observed for some occupations: waiter (OR = 2.94, 1.11–7.78), charworker (OR = 3.02, 1.38–6.60), electrical and electronic equipment assembler (OR = 7.16, 2.02–25.38), plumber (OR = 3.95, 1.33–11.67), electric arc welder (OR = 6.15, 1.76–21.48), sheet-metal worker (OR = 2.89, 1.01–8.32), building painter (OR = 3.42, 1.01–11.49), and material handling equipment operator (OR = 5.05, 1.71–14.84). Results for industries were consistent with those observed for occupations. Conclusion: Our results showed that a history of head and neck cancer, cervicofacial radiotherapy, and several occupations and industries, were associated with an increased risk of SGC. Further studies with larger sample sizes are indicated to confirm our results. © 2018
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|a adult
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|a adverse event
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|a aged
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|a alcohol
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|a alcohol consumption
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|a Alcohol Drinking
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|a Article
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|a case control study
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|a Case-Control Studies
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|a cervicofacial radiotherapy
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|a charworker
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|a controlled study
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|a drinking behavior
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|a electric arc welder
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|a electrical and electronic equipment assembler
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|a Epidemiologic studies
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|a family history
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|a female
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|a Female
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|a France
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|a head and neck cancer
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|a Head and neck cancers
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|a Head and Neck Neoplasms
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|a head and neck tumor
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|a human
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|a Humans
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|a Industry
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|a Life style
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|a lifespan
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|a lifestyle
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|a major clinical study
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|a male
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|a Male
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|a material handling equipment operator
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|a medical history
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|a middle aged
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|a Middle Aged
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|a multicenter study
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|a nonmedical occupations
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|a occupation
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|a occupational hazard
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|a Occupations
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|a operator
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|a painter
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|a plumber
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|a population based case control study
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|a priority journal
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|a radiotherapy
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|a Radiotherapy
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|a risk factor
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|a Risk factors
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|a Risk Factors
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|a salivary gland cancer
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|a Salivary gland neoplasms
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|a Salivary Gland Neoplasms
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|a salivary gland tumor
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|a sheet metal worker
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|a smoking
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|a Smoking
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|a tobacco use
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|a waiter
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|a Barul, C.
|e author
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|a Carton, M.
|e author
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|a ICARE Study Group
|e author
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|a Luce, D.
|e author
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|a Matrat, M.
|e author
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|a Menvielle, G.
|e author
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|a Pilorget, C.
|e author
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|a Radoï, L.
|e author
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|a Sanchez, M.
|e author
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|a Stücker, I.
|e author
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|a Velten, M.
|e author
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773 |
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|t Oral Oncology
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