Metabolic modelling reveals broad changes in gut microbial metabolism in inflammatory bowel disease patients with dysbiosis

Inflammatory bowel diseases, such as Crohn’s Disease, are characterised by an altered blood and faecal metabolome, and changes in gut microbiome composition. Here, we present an efficient, scalable, tractable systems biology framework to mechanistically link microbial strains and faecal metabolites....

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Bibliographic Details
Main Authors: Heinken, A. (Author), Hertel, J. (Author), Thiele, I. (Author)
Format: Article
Language:English
Published: Nature Research 2021
Subjects:
Online Access:View Fulltext in Publisher