Maladaptive myelination promotes generalized epilepsy progression

Maladaptive myelination promotes generalized epilepsy progression

Activity-dependent myelination can fine-tune neural network dynamics. Conversely, aberrant neuronal activity, as occurs in disorders of recurrent seizures (epilepsy), could promote maladaptive myelination, contributing to pathogenesis. In this study, we tested the hypothesis that activity-dependent...

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Bibliographic Details
Main Authors: Batra, A. (Author), Fraga, D. (Author), Frost, E. (Author), Huguenard, J.R (Author), Knowles, J.K (Author), Monje, M. (Author), Ni, L. (Author), Saucedo, T. (Author), Soane, C. (Author), Talmi, S. (Author), Tam, L.T (Author), Villar, K. (Author), Xu, H. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher

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