Safety of Proton Pump Inhibitors Based on a Large, Multi-Year, Randomized Trial of Patients Receiving Rivaroxaban or Aspirin

Background & Aims: Proton pump inhibitors (PPIs) are effective at treating acid-related disorders. These drugs are well tolerated in the short term, but long-term treatment was associated with adverse events in observational studies. We aimed to confirm these findings in an adequately powered ra...

Full description

Bibliographic Details
Main Authors:	Alings, M. (Author), Anand, S.S (Author), Avezum, A. (Author), Bhatt, D.L (Author), Bosch, J. (Author), Branch, K.R.H (Author), Bruns, N.C (Author), Commerford, P.J (Author), COMPASS Investigators (Author), Connolly, S.J (Author), Dagenais, G.R (Author), Dans, A.L (Author), Diaz, R. (Author), Dyal, L. (Author), Eikelboom, J.W (Author), Ertl, G. (Author), Felix, C. (Author), Fox, K.A.A (Author), Guzik, T.J (Author), Hart, R.G (Author), Hori, M. (Author), Kakkar, A.K (Author), Keltai, M. (Author), Kim, J.-H (Author), Lanas, F. (Author), Leong, D. (Author), Lewis, B.S (Author), Liang, Y. (Author), Lonn, E.M (Author), Lopez-Jaramillo, P. (Author), Maggioni, A.P (Author), Metsarinne, K.P (Author), Moayyedi, P. (Author), Muehlhofer, E. (Author), O'Donnell, M. (Author), Parkhomenko, A.N (Author), Piegas, L.S (Author), Pogosova, N. (Author), Probstfield, J. (Author), Ryden, L. (Author), Shestakovska, O. (Author), Steg, P.G (Author), Störk, S. (Author), Tonkin, A.M (Author), Torp-Pedersen, C. (Author), Verhamme, P.B (Author), Vinereanu, D. (Author), Widimsky, P. (Author), Yusoff, K. (Author), Yusuf, S. (Author), Zhu, J. (Author)
Format:	Article
Language:	English
Published:	W.B. Saunders 2019
Subjects:	acetylsalicylic acid aged Aged all cause mortality antithrombocytic agent Article Aspirin Bacteria blood clotting factor 10a inhibitor cardiovascular disease Cardiovascular Diseases cardiovascular mortality cerebrovascular accident chronic kidney failure chronic obstructive lung disease clinical trial Clostridium difficile infection controlled study CVD dementia diabetes mellitus double blind procedure Double-Blind Method drug administration Drug Administration Schedule drug efficacy drug safety Enterocolitis, Pseudomembranous Factor Xa Inhibitors female Female follow up fracture gastrointestinal disease gastrointestinal hemorrhage Gastrointestinal Hemorrhage heart infarction hospitalization human Humans intestine infection low drug dose major clinical study male Male malignant neoplasm microbiology middle aged Middle Aged multicenter study pantoprazole Pantoprazole Peripheral Arterial Disease peripheral occlusive artery disease placebo Platelet Aggregation Inhibitors pneumonia priority journal Prospective Studies prospective study proton pump inhibitor Proton Pump Inhibitors pseudomembranous colitis randomized controlled trial Reflux risk assessment Risk Assessment risk factor Risk Factors rivaroxaban Rivaroxaban Thrombosis time factor Time Factors treatment outcome Treatment Outcome
Online Access:	View Fulltext in Publisher View in Scopus

Internet

View Fulltext in Publisher
View in Scopus

Safety of Proton Pump Inhibitors Based on a Large, Multi-Year, Randomized Trial of Patients Receiving Rivaroxaban or Aspirin

Internet

Similar Items