N6-methyladenosine (m6A) reader IGF2BP2 promotes gastric cancer progression via targeting SIRT1

N6-methyladenosine (m6A) reader IGF2BP2 promotes gastric cancer progression via targeting SIRT1

N6-methyladenosine (m6A) modification acts as the most prevalent internal modification in eukaryotic mRNA. Emerging evidence shows the critical biological roles of m6A key enzymes in human cancers. However, the roles of m6A binding protein IGF2BP2 in gastric cancer (GC) progression are still unclear...

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Bibliographic Details
Main Authors: Gao, W. (Author), Li, T. (Author), Shi, J. (Author), Song, W. (Author), Xing, Y. (Author), Yang, L. (Author), Zhang, Z. (Author)
Format: Article
Language:English
Published: Taylor and Francis Ltd. 2022
Subjects:
adenosine
Adenosine
Cell Line, Tumor
Gastric cancer
gene expression regulation
Gene Expression Regulation, Neoplastic
genetics
human
Humans
IGF2BP2
IGF2BP2 protein, human
messenger RNA
metabolism
N6-methyladenosine
N-methyladenosine
pathology
RNA binding protein
RNA, Messenger
RNA-Binding Proteins
SIRT1
SIRT1 protein, human
sirtuin 1
Sirtuin 1
Stomach Neoplasms
stomach tumor
tumor cell line
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