Impact of clinical decision support therapeutic interchanges on hospital discharge medication omissions and duplications

Purpose: Automatic therapeutic substitution (ATS) protocols are formulary tools that allow for provider-selected interchange from a nonformulary preadmission medication to a formulary equivalent. Previous studies have demonstrated that the application of clinical decision support (CDS) tools to ATS...

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Bibliographic Details
Main Authors: Amerine, J. (Author), Carlton, G. (Author), Cruz, J.L (Author), Heindel, G.A (Author), Maxwell, E. (Author), Pappas, A.L (Author)
Format: Article
Language:English
Published: Oxford University Press 2021
Subjects:
Online Access:View Fulltext in Publisher
LEADER 03557nam a2200517Ia 4500
001 10.1093-ajhp-zxab219
008 220427s2021 CNT 000 0 und d
020 |a 10792082 (ISSN) 
245 1 0 |a Impact of clinical decision support therapeutic interchanges on hospital discharge medication omissions and duplications 
260 0 |b Oxford University Press  |c 2021 
856 |z View Fulltext in Publisher  |u https://doi.org/10.1093/ajhp/zxab219 
520 3 |a Purpose: Automatic therapeutic substitution (ATS) protocols are formulary tools that allow for provider-selected interchange from a nonformulary preadmission medication to a formulary equivalent. Previous studies have demonstrated that the application of clinical decision support (CDS) tools to ATS can decrease ATS errors at admission, but there are limited data describing the impact of CDS on discharge errors. The objective of this study was to describe the impact of CDS-supported interchanges on discharge prescription duplications or omissions. Methods: This was a single-center, retrospective cohort study conducted at an academic medical center. Patients admitted between June 2017 and August 2019 were included if they were 18 years or older at admission, underwent an ATS protocol-approved interchange for 1 of the 9 included medication classes, and had a completed discharge medication reconciliation. The primary outcome was difference in incidence of therapeutic duplication or omission at discharge between the periods before and after CDS implementation. Results: A total of 737 preimplementation encounters and 733 postimplementation encounters were included. CDS did not significantly decrease the incidence of discharge duplications or omissions (12.1% vs 11.2%; 95% confidence interval [CI], -2.3% to 4.2%) nor the incidence of admission duplication or inappropriate reconciliation (21.4% vs 20.7%; 95% CI, -3.4% to 4.8%) when comparing the pre- and postimplementation periods. Inappropriate reconciliation was the primary cause of discharge medication errors for both groups. Conclusion: CDS implementation was not associated with a decrease in discharge omissions, duplications, or inappropriate reconciliation. Findings highlight the need for thoughtful medication reconciliation at the point of discharge. © 2021 American Society of Health-System Pharmacists 2021. All rights reserved. 
650 0 4 |a adult 
650 0 4 |a article 
650 0 4 |a clinical decision support system 
650 0 4 |a cohort analysis 
650 0 4 |a decision support system 
650 0 4 |a Decision Support Systems, Clinical 
650 0 4 |a formulary stewardship 
650 0 4 |a hospital 
650 0 4 |a hospital discharge 
650 0 4 |a Hospitals 
650 0 4 |a human 
650 0 4 |a Humans 
650 0 4 |a incidence 
650 0 4 |a medication error 
650 0 4 |a medication reconciliation 
650 0 4 |a Medication Reconciliation 
650 0 4 |a medication therapy management 
650 0 4 |a medication therapy management 
650 0 4 |a medication-use policy 
650 0 4 |a outcome assessment 
650 0 4 |a Patient Discharge 
650 0 4 |a pharmacy technology 
650 0 4 |a prescription 
650 0 4 |a Retrospective Studies 
650 0 4 |a retrospective study 
650 0 4 |a therapeutic interchange 
650 0 4 |a university hospital 
700 1 |a Amerine, J.  |e author 
700 1 |a Carlton, G.  |e author 
700 1 |a Cruz, J.L.  |e author 
700 1 |a Heindel, G.A.  |e author 
700 1 |a Maxwell, E.  |e author 
700 1 |a Pappas, A.L.  |e author 
773 |t American Journal of Health-System Pharmacy