Nebulosa recovers single-cell gene expression signals by kernel density estimation

Data sparsity in single-cell experiments prevents an accurate assessment of gene expression when visualized in a low-dimensional space. Here, we introduce Nebulosa, an R package that uses weighted kernel density estimation to recover signals lost through drop-out or low expression. Availability and...

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Bibliographic Details
Main Authors: Alquicira-Hernandez, J. (Author), Powell, J.E (Author)
Format: Article
Language:English
Published: Oxford University Press 2021
Subjects:
Online Access:View Fulltext in Publisher
LEADER 01119nam a2200169Ia 4500
001 10.1093-bioinformatics-btab003
008 220427s2021 CNT 000 0 und d
020 |a 13674803 (ISSN) 
245 1 0 |a Nebulosa recovers single-cell gene expression signals by kernel density estimation 
260 0 |b Oxford University Press  |c 2021 
856 |z View Fulltext in Publisher  |u https://doi.org/10.1093/bioinformatics/btab003 
520 3 |a Data sparsity in single-cell experiments prevents an accurate assessment of gene expression when visualized in a low-dimensional space. Here, we introduce Nebulosa, an R package that uses weighted kernel density estimation to recover signals lost through drop-out or low expression. Availability and implementation: Nebulosa can be easily installed from www.github.com/powellgenomicslab/Nebulosa. © The Author(s) 2021. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. 
650 0 4 |a article 
650 0 4 |a gene expression 
700 1 |a Alquicira-Hernandez, J.  |e author 
700 1 |a Powell, J.E.  |e author 
773 |t Bioinformatics