Big Data and the Precision Medicine Revolution

The big data revolution is making vast amounts of information available in all sectors of the economy including health care. One important type of data that is particularly relevant to medicine is observational data from actual practice. In comparison to experimental data from clinical studies, obse...

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Bibliographic Details
Main Authors: Hopp, W.J (Author), Li, J. (Author), Wang, G. (Author)
Format: Article
Language:English
Published: Wiley-Blackwell 2018
Subjects:
Online Access:View Fulltext in Publisher
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008 220706s2018 CNT 000 0 und d
020 |a 10591478 (ISSN) 
245 1 0 |a Big Data and the Precision Medicine Revolution 
260 0 |b Wiley-Blackwell  |c 2018 
856 |z View Fulltext in Publisher  |u https://doi.org/10.1111/poms.12891 
520 3 |a The big data revolution is making vast amounts of information available in all sectors of the economy including health care. One important type of data that is particularly relevant to medicine is observational data from actual practice. In comparison to experimental data from clinical studies, observational data offers much larger sample sizes and much broader coverage of patient variables. Properly combining observational data with experimental data can facilitate precision medicine by enabling detection of heterogeneity in patient responses to treatments and tailoring of health care to the specific needs of individuals. However, because it is high-dimensional and uncontrolled, observational data presents unique methodological challenges. The modeling and analysis tools of the production and operations management field are well-suited to these challenges and hence POM scholars are critical to the realization of precision medicine with its many benefits to society. © 2018 Production and Operations Management Society 
650 0 4 |a big data 
650 0 4 |a causal inference 
650 0 4 |a machine learning 
650 0 4 |a observational data 
650 0 4 |a precision medicine 
700 1 |a Hopp, W.J.  |e author 
700 1 |a Li, J.  |e author 
700 1 |a Wang, G.  |e author 
773 |t Production and Operations Management