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01951nam a2200229Ia 4500 |
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10.1136-bcr-2022-249094 |
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220718s2022 CNT 000 0 und d |
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|a 1757790X (ISSN)
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|a Case of adult-onset Kawasaki disease and multisystem inflammatory syndrome following SARS-CoV-2 vaccination
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|b NLM (Medline)
|c 2022
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|z View Fulltext in Publisher
|u https://doi.org/10.1136/bcr-2022-249094
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|a Kawasaki disease (KD) and multisystem inflammatory syndrome (MIS) are rare conditions that occur predominately in children. Recent reports document KD and MIS in adult patients following infection with SARS-CoV-2. Rarely, MIS is observed following vaccination against SARS-CoV-2, mostly in patients with prior SARS-CoV-2 infection. We report a case of KD in a man after a second SARS-CoV-2 vaccine dose, in absence of concurrent or prior SARS-CoV-2 infection. This patient also met criteria for probable MIS associated with vaccination. He tested negative for SARS-CoV-2 RNA via reverse transcriptase PCR, negative for SARS-CoV-2 nucleocapsid antibodies and demonstrated high levels SARS-CoV-2 spike protein antibodies, commonly used to assess vaccine response. Symptom improvement followed treatment with intravenous immunoglobulin, including desquamation of the hands and feet. As widespread vaccination against SARS-CoV-2 continues, increased vigilance and prompt intervention is necessary to limit the effects of postvaccination inflammatory syndromes. © BMJ Publishing Group Limited 2022. No commercial re-use. See rights and permissions. Published by BMJ.
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|a COVID-19
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|a Immunological products and vaccines
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|a Rheumatology
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|a Unwanted effects / adverse reactions
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|a Vaccination/immunisation
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|a Khakshour, D.
|e author
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|a Maurer, J.M.
|e author
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|a Showers, C.R.
|e author
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|a Shukla, M.
|e author
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|t BMJ case reports
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