Long-Term Visual Outcomes of Primary Congenital Glaucoma in China

Long-Term Visual Outcomes of Primary Congenital Glaucoma in China

Introduction: The aim of this study was to investigate the long-term visual outcomes and factors associated with vision loss in Chinese patients with primary congenital glaucoma (PCG) after successful intraocular pressure (IOP) control (IOP ≤21 mm Hg). Methods: PCG patients with IOP control who were...

Full description

Bibliographic Details
Main Authors: Fang, L. (Author), Hu, Y. (Author), Lin, S. (Author), Liu, X. (Author), Su, Y. (Author), Xiao, H. (Author), Zhong, Y. (Author), Zhu, Y. (Author)
Format: Article
Language:English
Published: S. Karger AG 2022
Subjects:
amblyopia
Amblyopia
child
Child
complication
follow up
Follow-Up Studies
glaucoma
Glaucoma
human
Humans
intraocular pressure
Intraocular Pressure
Outcome
Primary congenital glaucoma
procedures
Retrospective Studies
retrospective study
Risk factor
trabeculectomy
Trabeculectomy
treatment outcome
Treatment Outcome
Vision Disorders
visual acuity
Visual acuity
Visual Acuity
visual disorder
Online Access:View Fulltext in Publisher
Description
Summary:Introduction: The aim of this study was to investigate the long-term visual outcomes and factors associated with vision loss in Chinese patients with primary congenital glaucoma (PCG) after successful intraocular pressure (IOP) control (IOP ≤21 mm Hg). Methods: PCG patients with IOP control who were examined in the glaucoma clinic at Zhongshan Ophthalmic Center from 2019 to 2020 were enrolled. The final visual outcome was evaluated by the best corrected visual acuity (VA). Univariate and multivariate analyses were used to investigate the associations of visual impairment with potential risk factors. The causes for decreased VA (<20/50) were also analyzed. Results: Fifty-nine patients (95 eyes) were included in the cohort, with a mean age of 8.7 years. The mean logMAR VA was 0.62 ± 0.64. The VAs of eyes treated for PCG were good (≥20/50) in 56%, fair (20/60-20/200) in 30%, and poor (<20/200) in 14%. The most common cause of decreased VA was amblyopia (64.3%). Multivariate logistic regression analysis showed that undergoing multiple surgeries (OR: 4.86, 95% CI: 1.11-21.16, p = 0.035) was significantly associated with visual impairment. Conclusion: The results showed that good VA was attainable in approximately half of PCG eyes under IOP control. Prompt and effective treatment of PCG, management of amblyopia and ocular comorbidities may be potential steps toward achieving good visual outcomes in PCG patients. © 2022
ISBN:00303747 (ISSN)
DOI:10.1159/000523939

Similar Items