Herbal supplements and hepatotoxicity: A short review
Herbal products have gained popularity over the past few decades. The reasons attributed to the rise in popularity are cheaper costs, easy availability, patient compliance and fewer side effects. However, liver toxicity following consumption of herbal remedies is on the increase. Thus, there is an u...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Natural Product Incorporation
2015
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| Subjects: | |
| Online Access: | View Fulltext in Publisher View in Scopus |
| LEADER | 03398nam a2200853Ia 4500 | ||
|---|---|---|---|
| 001 | 10.1177-1934578x1501001035 | ||
| 008 | 220112s2015 CNT 000 0 und d | ||
| 020 | |a 1934578X (ISSN) | ||
| 245 | 1 | 0 | |a Herbal supplements and hepatotoxicity: A short review |
| 260 | 0 | |b Natural Product Incorporation |c 2015 | |
| 856 | |z View Fulltext in Publisher |u https://doi.org/10.1177/1934578x1501001035 | ||
| 856 | |z View in Scopus |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-84954199345&doi=10.1177%2f1934578x1501001035&partnerID=40&md5=b5c795721a86814c80ff62d2749051d1 | ||
| 520 | 3 | |a Herbal products have gained popularity over the past few decades. The reasons attributed to the rise in popularity are cheaper costs, easy availability, patient compliance and fewer side effects. However, liver toxicity following consumption of herbal remedies is on the increase. Thus, there is an urgent need to understand the mechanism of action of the herbal supplements on the liver. Occasionally, herbal supplements may also interact with conventional drugs. The present review focusses on a few herbs such as Aloe barbadensis, Atractylis gummifera, Centella asiatica, Mitragyna speciosa, Morinda citrifolia, Larea tridentata, Symphytum officinale, Teucrium chamaedrys and Xanthium strumarium, which are reported to cause hepatotoxicity in humans and animals. Prior knowledge on hepatotoxicity caused by herbs may be beneficial for clinicians and medical practitioners. | |
| 650 | 0 | 4 | |a acute hepatitis |
| 650 | 0 | 4 | |a Aloe vera |
| 650 | 0 | 4 | |a Alternative medicine |
| 650 | 0 | 4 | |a anthraquinone derivative |
| 650 | 0 | 4 | |a ascites |
| 650 | 0 | 4 | |a asiatic acid |
| 650 | 0 | 4 | |a Asteraceae |
| 650 | 0 | 4 | |a Atractylis gummifera |
| 650 | 0 | 4 | |a atractyloside |
| 650 | 0 | 4 | |a carboxyatractyloside |
| 650 | 0 | 4 | |a Centella asiatica |
| 650 | 0 | 4 | |a cholestatic hepatitis |
| 650 | 0 | 4 | |a chronic hepatitis |
| 650 | 0 | 4 | |a comfrey |
| 650 | 0 | 4 | |a Complementary medicine |
| 650 | 0 | 4 | |a cytochrome P450 2E1 |
| 650 | 0 | 4 | |a diet supplementation |
| 650 | 0 | 4 | |a Dietary Supplements |
| 650 | 0 | 4 | |a Drug-Induced Liver Injury |
| 650 | 0 | 4 | |a fatty liver |
| 650 | 0 | 4 | |a germander |
| 650 | 0 | 4 | |a granulomatous hepatitis |
| 650 | 0 | 4 | |a herbaceous agent |
| 650 | 0 | 4 | |a Herbs |
| 650 | 0 | 4 | |a human |
| 650 | 0 | 4 | |a Humans |
| 650 | 0 | 4 | |a hypertransaminasemia |
| 650 | 0 | 4 | |a jaundice |
| 650 | 0 | 4 | |a Lamiaceae |
| 650 | 0 | 4 | |a Larrea tridentata |
| 650 | 0 | 4 | |a Liver |
| 650 | 0 | 4 | |a liver cirrhosis |
| 650 | 0 | 4 | |a liver disease |
| 650 | 0 | 4 | |a liver fibrosis |
| 650 | 0 | 4 | |a liver necrosis |
| 650 | 0 | 4 | |a liver toxicity |
| 650 | 0 | 4 | |a liver venoocclusive disease |
| 650 | 0 | 4 | |a Mitragyna speciosa |
| 650 | 0 | 4 | |a mitragynine |
| 650 | 0 | 4 | |a Morinda citrifolia |
| 650 | 0 | 4 | |a multiple organ failure |
| 650 | 0 | 4 | |a nonhuman |
| 650 | 0 | 4 | |a nordihydroguaiaretic acid |
| 650 | 0 | 4 | |a pathology |
| 650 | 0 | 4 | |a plant medicinal product |
| 650 | 0 | 4 | |a Plant Preparations |
| 650 | 0 | 4 | |a Plants, Toxic |
| 650 | 0 | 4 | |a poisonous plant |
| 650 | 0 | 4 | |a Review |
| 650 | 0 | 4 | |a Rubiaceae |
| 650 | 0 | 4 | |a Teucrium chamaedrys |
| 650 | 0 | 4 | |a toxic hepatitis |
| 650 | 0 | 4 | |a toxicity |
| 650 | 0 | 4 | |a Toxicity |
| 650 | 0 | 4 | |a Xanthium strumarium |
| 650 | 0 | 4 | |a xenobiotic metabolism |
| 650 | 0 | 4 | |a Zygophyllaceae |
| 700 | 1 | 0 | |a Das, S. |e author |
| 700 | 1 | 0 | |a Haslan, H. |e author |
| 700 | 1 | 0 | |a Suhaimi, F.H. |e author |
| 773 | |t Natural Product Communications | ||