Quantitative proteomics reveals protein dysregulation during T cell activation in multiple sclerosis patients compared to healthy controls

Quantitative proteomics reveals protein dysregulation during T cell activation in multiple sclerosis patients compared to healthy controls

Background: Multiple sclerosis (MS) is an autoimmune, neurodegenerative disorder with a strong genetic component that acts in a complex interaction with environmental factors for disease development. CD4+ T cells are pivotal players in MS pathogenesis, where peripherally activated T cells migrate to...

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Bibliographic Details
Main Authors: Berge, T. (Author), Berven, F. (Author), Bos, S.D (Author), Brorson, I.S (Author), Cappelletti, C. (Author), Eriksson, A. (Author), Harbo, H.F (Author), Høgestøl, E.A (Author), Kråbøl, O. (Author), Leikfoss, I.S (Author), Mjaavatten, O. (Author), Vitelli, V. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
Autoimmunity
Disease susceptibility genes
Multiple sclerosis
Proteomics
T cell activation
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