FiNGS: high quality somatic mutations using filters for next generation sequencing

Background: Somatic variant callers are used to find mutations in sequencing data from cancer samples. They are very sensitive and have high recall, but also may produce low precision data with a large proportion of false positives. Further ad hoc filtering is commonly performed after variant callin...

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Bibliographic Details
Main Authors: Ashby, C. (Author), Bauer, M.A (Author), Wardell, C.P (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
DNA
Online Access:View Fulltext in Publisher