WEScover: selection between clinical whole exome sequencing and gene panel testing

WEScover: selection between clinical whole exome sequencing and gene panel testing

Background: Whole exome sequencing (WES) is widely adopted in clinical and research settings; however, one of the practical concerns is the potential false negatives due to incomplete breadth and depth of coverage for several exons in clinically implicated genes. In some cases, a targeted gene panel...

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Bibliographic Details
Main Authors:	Alvarez, W.J (Author), Hernandez-Ferrer, C. (Author), Kong, S.W (Author), Lee, I.-H (Author), Lin, Y. (Author), Mandl, K.D (Author)
Format:	Article
Language:	English
Published:	BioMed Central Ltd 2021
Subjects:	Candidate genes Clinical research Coverage exome Exome False negative False negatives Gene panel testing Genes Genetic testing genetics genomics Genomics high throughput sequencing High-Throughput Nucleotide Sequencing Intuitive user interface Panel tests phenotype Phenotype Query processing True negative User interfaces WEB application Web-based tools whole exome sequencing Whole exome sequencing Whole Exome Sequencing
Online Access:	View Fulltext in Publisher

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