Mechanisms of gastroprotection of methanol extract of Melastoma malabathricum leaves

Mechanisms of gastroprotection of methanol extract of Melastoma malabathricum leaves

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Background: Melastoma malabathricum L. (Melastomaceae) is a small shrub with various medicinal uses. The present study was carried out to determine the gastroprotective mechanisms of methanol extract of M. malabathricum leaves (MEMM) in rats. Methods: The extract's mechanisms of gastroprotectio...

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Bibliographic Details
Main Authors: Balan, T. (Author), Kek, T.L (Author), Mamat, S.S (Author), Mohtarrudin, N. (Author), Salleh, M.Z (Author), Zakaria, Z.A (Author)
Format: Article
Language:English
Published: BioMed Central Ltd. 2015
Subjects:
animal
animal cell
animal experiment
animal model
animal tissue
Animals
Anti-inflammatory
antiinflammatory activity
Antioxidant
antioxidant activity
Article
carbenoxolone
catalase
cell viability
chemistry
controlled study
drug dose comparison
drug effects
ethanol-induced gastric ulcer
Gastric Juice
gastrointestinal mucosa protective agent
Gastroprotective mechanisms
glutathione peroxidase
glutathione reductase
high performance liquid chromatography
in vitro study
lipoxygenase
macrophage
male
Male
medicinal plant
Melastoma malabathricum
Melastoma malabathricum extract
Melastomaceae
Melastomataceae
methanol
Methanol
Methanol extract
myeloperoxidase
n(g) nitroarginine methyl ester
nitric oxide
Nitric oxide
nonhuman
plant extract
Plant Extracts
plant leaf
Plant Leaves
protective agent
Protective Agents
pylorus ligation induced gastric ulcer
quercitrin
ranitidine
rat
Rats
Rats, Sprague-Dawley
Sprague Dawley rat
stomach
Stomach
stomach juice
stomach mucus
stomach pH
stomach protection
Sulfhydryl group
superoxide dismutase
thiobarbituric acid reactive substance
thiol derivative
unclassified drug
xanthine oxidase
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