Extensive facial trichoblastoma – A rare and disfiguring condition

• Main Authors: Ahmad, N.A (Author), Mohamed-Yassin, M.-S (Author), Rahim, S.N.H.A (Author)
• Format: Article
• Language: English
• Published: International Scientific Information, Inc. 2021
• Series: American Journal of Case Reports
• Subjects: Adnexal and Skin Appendage • Trichoepitheliomas; adult; amlodipine; Article; atorvastatin; Basal Cell Carcinoma; bedtime dosage; blood pressure; body mass; dermatologist; diabetes mellitus; epidermoid cyst; Facial Trichoblastoma; female; gliclazide; glycemic control; human; human cell; hypertension; laser therapy; lipid blood level; metformin; middle aged; Multiple • Neoplasms; Multiple Desmoplastic; papule; perindopril; pulse rate; skin defect; trichoblastoma
• Online Access: View Fulltext in Publisher; View in Scopus

 Background: Trichoblastoma is a rare, benign, cutaneous adnexal neoplasm arising from rudimentary hair follicles. The incidence and prevalence in the general population is unknown. However, most cases occur in adults aged 40 years and older. Case Report: A 62-year-old woman presented to our primary care clinic for a hypertension and diabetes followup visit. The doctor, who had never seen the patient before, noticed several small lumps over the patient’s eyebrows. After she removed her headscarf and face mask for a thorough examination, numerous skin-colored papules and nodules were seen on her nose, nasal bridge, forehead, and around her eyebrows. She was referred to a dermatologist, and a skin biopsy showed well-circumscribed dermal nests of basaloid cells, with peripheral palisading, and keratin horn cysts surrounded by dense fibrous stroma. These features were consistent with trichoblastoma. She was then referred to a plastic surgeon to discuss further management options. The patient finally chose laser ablation as she was fearful of the other more invasive surgical options. Conclusions: This is a very rare case of extensive facial trichoblastoma. It highlights the need for clinicians to ensure optimal exposure when examining patients. It also highlights the role of biopsies for skin lesions of uncertain etiology. In this case, it helped to rule out basal cell carcinoma, which can be a more locally destructive condition than trichoblastoma. This case also serves as a reminder about the need for ongoing review and referral for further management for conditions for which previous treatment was unsuccessful. © Am J Case Rep, 2021.