Evaluating the effectiveness of ensemble voting in improving the accuracy of consensus signals produced by various DTWA algorithms from step-current signals generated during nanopore sequencing

Evaluating the effectiveness of ensemble voting in improving the accuracy of consensus signals produced by various DTWA algorithms from step-current signals generated during nanopore sequencing

Nanopore sequencing device analysis systems simultaneously generate multiple picoamperage current signals representing the passage of DNA or RNA nucleotides ratcheted through a biomolecule nanopore array by motor proteins. Squiggles are a noisy and time-distorted representation of an underlying nucl...

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Bibliographic Details
Main Authors: Chan, R. (Author), Gordon, P.M.K (Author), Khurram, M. (Author), Smith, M. (Author)
Format: Article
Language:English
Published: Public Library of Science 2021
Subjects:
algorithm
Algorithms
Article
artifact
averaging
biology
chemical modification
comparative effectiveness
Computational Biology
computer model
computer simulation
Computer Simulation
consensus sequence
Consensus Sequence
dynamic time warping
enolase
entropy
epigenetics
genetics
gestational age
gray matter
human
least square analysis
Markov chain
measurement accuracy
medicinal chemistry
nanopore sequencing
Nanopore Sequencing
nucleotide
nucleotide sequence
Phosphopyruvate Hydratase
RNA
signal noise ratio
Signal-To-Noise Ratio
stochastic model
Stochastic Processes
whole genome sequencing
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