Predicting anti-cancer drug combination responses with a temporal cell state network model
Cancer chemotherapy combines multiple drugs, but predicting the effects of drug combinations on cancer cell proliferation remains challenging, even for simple in vitro systems. We hypothesized that by combining knowledge of single drug dose responses and cell state transition network dynamics, we co...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
NLM (Medline)
2023
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| Subjects: | |
| Online Access: | View Fulltext in Publisher View in Scopus |