An evaluation of dose equivalence between synchrotron microbeam radiation therapy and conventional broadbeam radiation using clonogenic and cell impedance assays

An evaluation of dose equivalence between synchrotron microbeam radiation therapy and conventional broadbeam radiation using clonogenic and cell impedance assays

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Background: High-dose synchrotron microbeam radiation therapy (MRT) has shown the potential to deliver improved outcomes over conventional broadbeam (BB) radiation therapy. To implement synchrotron MRT clinically for cancer treatment, it is necessary to undertake dose equivalence studies to identify...

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Bibliographic Details
Main Authors: Crosbie, J.C (Author), Ibahim, M.J (Author), Paiva, P. (Author), Rogers, P.A.W (Author), Stevenson, A.W (Author), Yang, Y. (Author), Zaitseva, M. (Author)
Format: Article
Language:English
Published: Public Library of Science 2014
Subjects:
animal
animal cell
Animals
article
Australia
bioassay
bioequivalence
Biological Assay
broadbeam radiation therapy
cell assay
cell clone
cell line
Cell Line, Tumor
cell proliferation
Cell Proliferation
cell survival
Cell Survival
Clone Cells
clonogenic assay
controlled study
dose equivalence
Dose-Response Relationship, Radiation
dosimetry
Electric Impedance
evaluation study
impedance
in vitro study
Mice
microbeam radiation therapy
mouse
nonhuman
procedures
radiation dose
radiation response
radiotherapy
real time cell impedance sensing assay
synchrotron
synchrotron radiation
Synchrotrons
therapeutic equivalence
Therapeutic Equivalency
tumor cell line
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