Synthesis and antiurease & antioxidant activities of bis-Schiff bases of isophthalaldehyde
Bis-Schiff bases of iosophthalaldehyde were synthesized by reacting isophthalaldehyde with hydrazine hydrate in 1:2 ratio in ethanol for 2-3 h under reflux. Product of first step was again reacted in 1:2 ratio with different aldehyde or acetophenone yielding bis-Schiff bases (1-16). All compounds we...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Chemical Publishing Co.
2016
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| Subjects: | |
| Online Access: | View Fulltext in Publisher View in Scopus |
| LEADER | 01602nam a2200289Ia 4500 | ||
|---|---|---|---|
| 001 | 10.14233-ajchem.2016.19168 | ||
| 008 | 220120s2016 CNT 000 0 und d | ||
| 020 | |a 09707077 (ISSN) | ||
| 245 | 1 | 0 | |a Synthesis and antiurease & antioxidant activities of bis-Schiff bases of isophthalaldehyde |
| 260 | 0 | |b Chemical Publishing Co. |c 2016 | |
| 520 | 3 | |a Bis-Schiff bases of iosophthalaldehyde were synthesized by reacting isophthalaldehyde with hydrazine hydrate in 1:2 ratio in ethanol for 2-3 h under reflux. Product of first step was again reacted in 1:2 ratio with different aldehyde or acetophenone yielding bis-Schiff bases (1-16). All compounds were characterized by EI-MS and 1H NMR. All analogs were tested against antioxidant and urease inhibition. Few compounds were found to showed potent antiurease and antioxidant potential. | |
| 650 | 0 | 4 | |a Antioxidant potential |
| 650 | 0 | 4 | |a Isophthalaldehyde |
| 650 | 0 | 4 | |a Schiff bases |
| 650 | 0 | 4 | |a Urease inhibition |
| 700 | 1 | 0 | |a Abid, O.U.R. |e author |
| 700 | 1 | 0 | |a Khan, A. |e author |
| 700 | 1 | 0 | |a Quereshi, M.T. |e author |
| 700 | 1 | 0 | |a Rahim, F. |e author |
| 700 | 1 | 0 | |a Rehman, W. |e author |
| 700 | 1 | 0 | |a Shehzad, M. |e author |
| 700 | 1 | 0 | |a Taha, M. |e author |
| 700 | 1 | 0 | |a Tauseef, I. |e author |
| 700 | 1 | 0 | |a Waseeq-Ur-Rehamn |e author |
| 773 | |t Asian Journal of Chemistry |x 09707077 (ISSN) |g 28 1, 39-42 | ||
| 856 | |z View Fulltext in Publisher |u https://doi.org/10.14233/ajchem.2016.19168 | ||
| 856 | |z View in Scopus |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-84954126061&doi=10.14233%2fajchem.2016.19168&partnerID=40&md5=b087b7bde6d2a5b0d0c1c9993c1295a4 | ||