In-situ film-forming solution for topical application of terbinafine hcl: Biopharmaceutical evaluation and in vivo antifungal performance using animal model

In-situ film-forming solution for topical application of terbinafine hcl: Biopharmaceutical evaluation and in vivo antifungal performance using animal model

Objective: The main purpose of this study is to develop a film-forming solution with optimum physical-mechanical characteristics and excellent antifungal activity to enhance deposition and penetration into the stratum corneum (SC). Methods: The film-forming solutions of terbinafine HCl were formulat...

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Bibliographic Details
Main Authors:	Adam, A. (Author), Hasan, M.H (Author), Jaafar, N. (Author), Mustaffa, M.F (Author), Ramasamy, K. (Author), Ramli, N.A (Author), Suratman, S. (Author)
Format:	Article
Language:	English
Published:	Innovare Academics Sciences Pvt. Ltd 2021
Series:	International Journal of Applied Pharmaceutics
Subjects:	2 propanol alcohol animal experiment Antifungal antifungal activity Article chemical agent chloramphenicol controlled study crystallization dermatophyte Dermatophytes dermatophytosis drug bioavailability drug delivery system drug formulation Drug permeation drug release drug transport film forming solution fluconazole glass transition temperature glutamine high performance liquid chromatography hydroxypropylmethylcellulose In situ film-forming solution in vivo study ketamine nonhuman oligomer physical chemistry poly(acrylate methacrylate) rat skin defect stratum corneum Stratum corneum tensile strength terbex terbinafine Terbinafine HCL tiletamine Topical application Trichophyton rubrum unclassified drug xylazine zolazepam
Online Access:	View Fulltext in Publisher View in Scopus

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