Diabetes-Induced Cellular Senescence and Senescence-Associated Secretory Phenotype Impair Cardiac Regeneration and Function Independently of Age
Diabetes mellitus (DM) affects the biology of multipotent cardiac stem/progenitor cells (CSCs) and adult myocardial regeneration. We assessed the hypothesis that senescence and senescence-associated secretory phenotype (SASP) are main mechanisms of cardiac degenerative defect in DM. Accordingly, we...
Main Authors: | Cappetta, D. (Author), Cianflone, E. (Author), De Angelis, A. (Author), Ellison-Hughes, G.M (Author), Foti, D. (Author), Greco, M. (Author), Marino, F. (Author), Mastroroberto, P. (Author), Molinaro, C. (Author), Nadal-Ginard, B. (Author), Rossi, F. (Author), Rota, M. (Author), Salerno, L. (Author), Salerno, N. (Author), Sampaolesi, M. (Author), Sasso, F.C (Author), Scalise, M. (Author), Torella, D. (Author), Torella, M. (Author), Urbanek, K. (Author) |
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Format: | Article |
Language: | English |
Published: |
NLM (Medline)
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |
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