Acute application of Centella asiatica extract enhanced AMPAR-mediated postsynaptic currents in rat entorhinal cortex

Acute application of Centella asiatica extract enhanced AMPAR-mediated postsynaptic currents in rat entorhinal cortex

Centella asiatica is notable for its wide range of biological activities beneficial to human health, particularly its cognitive enhancement and neuroprotective effects. The-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors are ionotropic glutamate receptors mediating fast excitatory neuro...

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Bibliographic Details
Main Authors:	Abdullah, J.M (Author), Chuang, H.G (Author), Ismail, N.H (Author), Mohamad, H. (Author), Muhammad, T.S.T (Author), Muthuraju, S. (Author), Reza, F. (Author), Senik, M.H (Author), Wong, J.H (Author), Yusof, S.R (Author), Zhang, J. (Author)
Format:	Article
Language:	English
Published:	IMR Press Limited, 2020
Subjects:	alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid receptor AMPA receptor AMPAR animal animal experiment animal tissue Animals Article asiatic acid asiaticoside bioavailability brain slice Centella asiatica Centella asiatica extract cognition controlled study drug effect entorhinal cortex Entorhinal Cortex excitatory postsynaptic potential Excitatory Postsynaptic Potentials follow up hippocampus ionotropic receptor long term potentiation low drug dose male neuromodulation nonhuman nootropic agent Nootropic Agents patch clamp technique Patch-Clamp Techniques pyramidal nerve cell rat Rats Receptors, AMPA triterpene Triterpenes unclassified drug whole cell patch clamp whole-cell patch-clamp
Online Access:	View Fulltext in Publisher View in Scopus

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