Methicillin-resistant Staphylococcus aureus nasal carriage among patients and healthcare workers in a hospital in Kelantan, Malaysia

• Main Authors: Al-Talib, H. (Author), Hasan, H. (Author), Nmn, N.Z (Author), Ravichandran, M. (Author), Yean, C.Y (Author)
• Format: Article
• Language: English
• Published: Polish Society of Microbiologists 2013
• Subjects: antibiotic agent; article; bacterial colonization; bacterial genetics; bacterium isolate; bacterium isolation; disease carrier; drug use; female; genetic association; health care personnel; high risk population; hospital patient; human; length of stay; major clinical study; Malaysia; male; methicillin resistant Staphylococcus aureus; molecular phylogeny; MRSA; Nasal carriage; nasogastric tube; nonhuman; nose smear; Nosocomial infection; Staphylococcus aureus
• Online Access: View Fulltext in Publisher; View in Scopus
• ISBN: 17331331 (ISSN)
• DOI: 10.33073/pjm-2013-016

Staphylococcus aureus nasal carriage is a common source of nosocomial infection and colonization. The aim of the present study was to assess the burden of methicillin-resistant S. aureus nasal carriage, its association with factors of interest including its genetic relationships. The prevalence of S. aureus nasal carriage was found to be 28.7%. This study showed that patients with a history of previous antibiotic intake, nasogastric tube, and longer hospitalization had a significantly high risk of being MRSA nasal carriers. The genetic relationship of all 34 nasal MRSA isolates revealed four major clusters of isolates, and there was a relationship between MRSA isolated from inpatients and healthcare workers.