Unusual primary sphenoid adenoid cystic carcinoma: The importance of combined CT and MR evaluation
Objective: To report a diagnostic challenge of primary sphenoid adenoid cystic carcinoma. Case summary: A 60-year-old premorbid healthy lady presented with progressive deterioration of visual acuity of the left eye associated with diplopia, left epiphora and left ear blockage for two weeks duration....
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Ibn Sina Trust
2016
|
Subjects: | |
Online Access: | View Fulltext in Publisher View in Scopus |
LEADER | 03347nam a2200529Ia 4500 | ||
---|---|---|---|
001 | 10.3329-bjms.v15i2.27898 | ||
008 | 220120s2016 CNT 000 0 und d | ||
020 | |a 22234721 (ISSN) | ||
245 | 1 | 0 | |a Unusual primary sphenoid adenoid cystic carcinoma: The importance of combined CT and MR evaluation |
260 | 0 | |b Ibn Sina Trust |c 2016 | |
520 | 3 | |a Objective: To report a diagnostic challenge of primary sphenoid adenoid cystic carcinoma. Case summary: A 60-year-old premorbid healthy lady presented with progressive deterioration of visual acuity of the left eye associated with diplopia, left epiphora and left ear blockage for two weeks duration. Examination revealed a ‘non perception of light’ (NPL) of the left eye with left abducent nerve palsy. The nasoendoscopic findings were unremarkable. Initial computed tomography of the brain and paranasal sinus showed a large clivus tumor with intracranial extension while subsequent magnetic resonance detected the epicenter of the tumour appeared to be in the sphenoid sinus with extension to the surrounding structures. A transeptal transsphenoidal biopsy was done reported as mixed pattern adenoid cystic adenocarcinoma. Discussion: Primary sphenoid adenoid cystic carcinoma is an extremely rare slow growing malignancy with non-specific clinical symptoms. The neuro-ophthalmology symptoms are the main presentation. Combined computed tomography and magnetic resonance images are essential in establishing differential diagnosis and to delineate the extent of this disease. Combined modality of surgery and postoperative radiation for adenoid cystic carcinoma has proven better results. Conclusions: Primary sphenoid adenoid cystic carcinoma poses a diagnostic challenge clinically. Combined radiological characteristic from computed tomography and magnetic resonance images are essential to aid the diagnosis. © 2016, Ibn Sina Trust. All rights reserved. | |
650 | 0 | 4 | |a abducens nerve paralysis |
650 | 0 | 4 | |a adenocarcinoma |
650 | 0 | 4 | |a adenoid cystic carcinoma |
650 | 0 | 4 | |a Adenoid cystic carcinoma |
650 | 0 | 4 | |a adult |
650 | 0 | 4 | |a antineoplastic agent |
650 | 0 | 4 | |a Article |
650 | 0 | 4 | |a cancer palliative therapy |
650 | 0 | 4 | |a case report |
650 | 0 | 4 | |a chemoradiotherapy |
650 | 0 | 4 | |a chordoma |
650 | 0 | 4 | |a clival chordoma |
650 | 0 | 4 | |a computer assisted tomography |
650 | 0 | 4 | |a differential diagnosis |
650 | 0 | 4 | |a diplopia |
650 | 0 | 4 | |a epiphora |
650 | 0 | 4 | |a exophthalmos |
650 | 0 | 4 | |a female |
650 | 0 | 4 | |a headache |
650 | 0 | 4 | |a human |
650 | 0 | 4 | |a human tissue |
650 | 0 | 4 | |a middle aged |
650 | 0 | 4 | |a nuclear magnetic resonance imaging |
650 | 0 | 4 | |a primary sphenoid adenoid cystic carcinoma |
650 | 0 | 4 | |a Salivary gland carcinoma |
650 | 0 | 4 | |a Sphenoid primary |
650 | 0 | 4 | |a squamous cell carcinoma |
650 | 0 | 4 | |a tumor biopsy |
650 | 0 | 4 | |a visual acuity |
700 | 1 | 0 | |a Ali, N.D.M. |e author |
700 | 1 | 0 | |a Jaafar, R. |e author |
700 | 1 | 0 | |a Lazim, N.M. |e author |
700 | 1 | 0 | |a Soffian, M.S.M. |e author |
773 | |t Bangladesh Journal of Medical Science |x 22234721 (ISSN) |g 15 2, 297-302 | ||
856 | |z View Fulltext in Publisher |u https://doi.org/10.3329/bjms.v15i2.27898 | ||
856 | |z View in Scopus |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-84981525033&doi=10.3329%2fbjms.v15i2.27898&partnerID=40&md5=a4b47c7ff8565e03f20efb5cd1282374 |