A Novel Antimalarial Metabolite in Erythrocyte From the Hydroxylation of Dihydroartemisinin by Cunninghamella elegans
Dihydroartemisinin (DHA) is a sesquiterpene endoperoxide with prominent antimalarial efficacy, which was discovered by Professor Youyou Tu through the reduction of artemisinin in the 1970s. It is always a challenging work for scientists to investigate the metabolites of DHA in the red blood cells du...
Main Authors: | Bai, Y. (Author), Gao, X. (Author), Ma, Y. (Author), Sun, P. (Author), Yang, L. (Author), Zhang, D. (Author), Zhao, Y. (Author) |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022
|
Subjects: | |
Online Access: | View Fulltext in Publisher |
Similar Items
-
Population pharmacokinetics of artesunate and dihydroartemisinin in children and pregnant women with malaria
by: Morris, Carrie Ann
Published: (2014) -
An investigation of the auto-induction of and gender-related variability in the pharmacokinetics of dihydroartemisinin in the rat
by: Zhu Fanping, et al.
Published: (2012-11-01) -
Formulation of Dihydroartemisinin-Piperaquine (DHP) Generic Tablet as Antimalarials Drug
by: Nanang Yunarto, et al.
Published: (2016-09-01) -
Anti-malarial efficacy and resistance monitoring of artemether-lumefantrine and dihydroartemisinin-piperaquine shows inadequate efficacy in children in Burkina Faso, 2017–2018
by: Adama Gansané, et al.
Published: (2021-01-01) -
11βββ-Hydroxylation of Cortexolone (Reichstein’s Compound S) to Hydrocortisone Using Immobilized Cunninghamella elegans Spores
by: Allam, R. F., et al.
Published: (2011-01-01)