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10.3389-fnins.2022.855868 |
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|a 16624548 (ISSN)
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|a Brain Imaging Changes in Patients Recovered From COVID-19: A Narrative Review
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|b Frontiers Media S.A.
|c 2022
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|z View Fulltext in Publisher
|u https://doi.org/10.3389/fnins.2022.855868
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|a The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused several outbreaks of highly contagious respiratory diseases worldwide. The respiratory symptoms of Coronavirus Disease-19 (COVID-19) have been closely monitored and studied, while the central nervous system (CNS) and peripheral system (PNS) lesions induced by COVID-19 have not received much attention. Currently, patients with COVID-19-associated encephalopathy present with dizziness, headache, anxiety and depression, stroke, epileptic seizures, the Guillain-Barre syndrome (GBS), and demyelinating disease. The exact pathologic basis for these neurological symptoms is currently not known. Rapid mutation of the SARS-CoV-2 genome leads to the appearance of SARS-CoV-2 variants of concern (VOCs), which have higher infectivity and virulence. Therefore, this narrative review will focus on the imaging assessment of COVID-19 and its VOC. There has been an increase in technologies, such as [18F]fluorodeoxyglucose positron emission tomography (18F-FDG-PET) and functional magnetic resonance imaging (fMRI), that have been used to observe changes in brain microstructure over time in patients with COVID-19 recovery. Medical imaging and pathological approaches aimed at exploring the associations between COVID-19 and its VOC, with cranial nerve and abnormal nerve discharge will shed light on the rehabilitation process of brain microstructural changes related to SARS-CoV-2, and aid future research in our understanding of the treatment and prognosis of COVID-19 encephalopathy. Copyright © 2022 Huang, Ling, Manyande, Wu and Xiang.
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|a brain imaging
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|a COVID-19
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|a COVID-19 variants of concern
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|a magnetic resonance imaging
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|a SARS-CoV-2
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|a Huang, Y.
|e author
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|a Ling, Q.
|e author
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|a Manyande, A.
|e author
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|a Wu, D.
|e author
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|a Xiang, B.
|e author
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|t Frontiers in Neuroscience
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