Fluids Alter Elasticity Measurements: Porous Wave Propagation Accounts for Shear Wave Dispersion in Elastography

In shear wave elastography, rotational wave speeds are converted to elasticity measures using elastodynamic theory. The method has a wide range of applications and is the gold standard for non-invasive liver fibrosis detection. However, the observed shear wave dispersion of in vivo human liver shows...

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Bibliographic Details
Main Authors: Aichele, J. (Author), Catheline, S. (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2021
Subjects:
Online Access:View Fulltext in Publisher
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020 |a 2296424X (ISSN) 
245 1 0 |a Fluids Alter Elasticity Measurements: Porous Wave Propagation Accounts for Shear Wave Dispersion in Elastography 
260 0 |b Frontiers Media S.A.  |c 2021 
856 |z View Fulltext in Publisher  |u https://doi.org/10.3389/fphy.2021.697990 
520 3 |a In shear wave elastography, rotational wave speeds are converted to elasticity measures using elastodynamic theory. The method has a wide range of applications and is the gold standard for non-invasive liver fibrosis detection. However, the observed shear wave dispersion of in vivo human liver shows a mismatch with purely elastic and visco-elastic wave propagation theory. In a laboratory phantom experiment we demonstrate that porosity and fluid viscosity need to be considered to properly convert shear wave speeds to elasticity in soft porous materials. We extend this conclusion to the clinical application of liver stiffness characterization by revisiting in vivo studies of liver elastography. To that end we compare Biot’s theory of poro-visco-elastic wave propagation to Voigt’s visco-elastic model. Our results suggest that accounting for dispersion due to fluid viscosity could improve shear wave imaging in the liver and other highly vascularized organs. © Copyright © 2021 Aichele and Catheline. 
650 0 4 |a biot theory 
650 0 4 |a liver characterization 
650 0 4 |a poroelasticity 
650 0 4 |a shear wave dispersion 
650 0 4 |a shear wave elastography 
650 0 4 |a ultrasound imaging 
650 0 4 |a viscoelasticity 
650 0 4 |a voigt model 
700 1 |a Aichele, J.  |e author 
700 1 |a Catheline, S.  |e author 
773 |t Frontiers in Physics