Chloroquine-Induced DNA Damage Synergizes with Nonhomologous End Joining Inhibition to Cause Ovarian Cancer Cell Cytotoxicity
Ovarian cancer (OC) is the most lethal gynecological malignancy; therefore, more effective treatments are urgently needed. We recently reported that chloroquine (CQ) increased reactive oxygen species (ROS) in OC cell lines (OCCLs), causing DNA double-strand breaks (DSBs). Here, we analyzed whether t...
Main Authors: | de la Peña, M.C.V (Author), González-Sarmiento, R. (Author), Herrero, A.B (Author), Ovejero-Sánchez, M. (Author), Pérez-Losada, J. (Author), Rubio-Heras, J. (Author), San-Segundo, L. (Author) |
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Format: | Article |
Language: | English |
Published: |
MDPI
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |
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