Triazole Derivatives Target 14α–Demethylase (LDM) Enzyme in Candida albicans Causing Ergosterol Biosynthesis Inhibition

Triazole Derivatives Target 14α–Demethylase (LDM) Enzyme in Candida albicans Causing Ergosterol Biosynthesis Inhibition

Candida albicans is the most dominant and prevalent cause of fungal infections in humans. Azoles are considered as first-line drugs for the treatment of these infections. However, their prolonged and insistent use has led to multidrug resistance and treatment failures. To overcome this, modification...

Full description

Bibliographic Details
Main Authors: Ahmad, A. (Author), Asseri, A.H (Author), Rather, I.A (Author), Sabir, J.S.M (Author), Wani, M.Y (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
C. albicans
ergosterol
molecular docking
simulation
triazole derivatives
Online Access:View Fulltext in Publisher

Similar Items

Similar Items