Cytoprotective effect of benzyl N'-(5-Chloro-indol-3-ylmethylidene)- hydrazinecarbodithioate against ethanol-induced gastric mucosal injury in rats

Cytoprotective effect of benzyl N'-(5-Chloro-indol-3-ylmethylidene)- hydrazinecarbodithioate against ethanol-induced gastric mucosal injury in rats

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Indolic compounds have attracted a lot of attention due to their interesting biological properties. The present study was performed to evaluate the subacute toxicity and anti-ulcer activity of BClHC against ethanol-induced gastric ulcers. Experimental animal groups were orally pre-treated with diffe...

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Bibliographic Details
Main Authors: Ali, H.M (Author), Ameen, M. (Author), Hashim, H. (Author), Khaledi, H. (Author), Mughrabi, F.F (Author)
Format: Article
Language:English
Subjects:
alcohol
animal
Animals
antiulcer agent
Anti-Ulcer Agents
article
Benzyl Compounds
benzyl derivative
benzyl N' (5 chloro indol 3 yl methylidene) hydrazinecarbodithioate
benzyl N'-(5-chloro-indol-3-yl-methylidene)-hydrazinecarbodithioate
Benzyl N'-(5-chloroindol-3-ylmethylidene)hydrazinecarbodithioate
cell protection
chemically induced disorder
Cytoprotection
drug effect
Drug Evaluation, Preclinical
drug screening
Ethanol
female
Female
Gastric Mucosa
Gastric ulcer
glycoprotein
Glycoproteins
Histology
hydrazine derivative
Hydrazines
Indole
kidney
Kidney
liver
Liver
male
Male
metabolism
omeprazole
Omeprazole
pathology
pathophysiology
physiology
rat
Rats
Rats, Wistar
stomach mucosa
stomach ulcer
Stomach Ulcer
Wistar rat
Online Access:View Fulltext in Publisher
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