Crocodylus porosus gut bacteria: A possible source of novel metabolites
Crocodiles are remarkable animals that have the ability to endure extremely harsh conditions and can survive up to a 100 years while being exposed to noxious agents that are detrimental to Homo sapiens. Besides their immunity, we postulate that the microbial gut flora of crocodiles may produce subst...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021
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| Series: | Molecules
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| Subjects: | |
| Online Access: | View Fulltext in Publisher View in Scopus |
| LEADER | 02191nam a2200445Ia 4500 | ||
|---|---|---|---|
| 001 | 10.3390-molecules26164999 | ||
| 008 | 220121s2021 CNT 000 0 und d | ||
| 020 | |a 14203049 (ISSN) | ||
| 245 | 1 | 0 | |a Crocodylus porosus gut bacteria: A possible source of novel metabolites |
| 260 | 0 | |b MDPI AG |c 2021 | |
| 490 | 1 | |a Molecules | |
| 650 | 0 | 4 | |a Alligators and Crocodiles |
| 650 | 0 | 4 | |a animal |
| 650 | 0 | 4 | |a Animals |
| 650 | 0 | 4 | |a Bacteria |
| 650 | 0 | 4 | |a bacterium |
| 650 | 0 | 4 | |a Cell Line, Tumor |
| 650 | 0 | 4 | |a Crocodiles |
| 650 | 0 | 4 | |a crocodilian |
| 650 | 0 | 4 | |a Crocodilians |
| 650 | 0 | 4 | |a Crocodylus porosus |
| 650 | 0 | 4 | |a Gastrointestinal Microbiome |
| 650 | 0 | 4 | |a Gut microbiota |
| 650 | 0 | 4 | |a intestine flora |
| 650 | 0 | 4 | |a isolation and purification |
| 650 | 0 | 4 | |a metabolism |
| 650 | 0 | 4 | |a microbiology |
| 650 | 0 | 4 | |a Microbiome |
| 650 | 0 | 4 | |a Novel metabolites |
| 650 | 0 | 4 | |a tumor cell line |
| 856 | |z View Fulltext in Publisher |u https://doi.org/10.3390/molecules26164999 | ||
| 856 | |z View in Scopus |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113300942&doi=10.3390%2fmolecules26164999&partnerID=40&md5=11ad9fd936adce6e59872c7b29c59491 | ||
| 520 | 3 | |a Crocodiles are remarkable animals that have the ability to endure extremely harsh conditions and can survive up to a 100 years while being exposed to noxious agents that are detrimental to Homo sapiens. Besides their immunity, we postulate that the microbial gut flora of crocodiles may produce substances with protective effects. In this study, we isolated and characterized selected bacteria colonizing the gastrointestinal tract of Crocodylus porosus and demonstrated their inhibitory effects against three different cancerous cell lineages. Using liquid chromatography-mass spectrometry, several molecules were identified. For the first time, we report partial analyses of crocodile’s gut bacterial molecules. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. | |
| 700 | 1 | 0 | |a Anuar, T.S. |e author |
| 700 | 1 | 0 | |a Khan, N.A. |e author |
| 700 | 1 | 0 | |a Maciver, S.K. |e author |
| 700 | 1 | 0 | |a Sagathevan, K. |e author |
| 700 | 1 | 0 | |a Siddiqui, R. |e author |
| 700 | 1 | 0 | |a Soopramanien, M. |e author |
| 773 | |t Molecules | ||