Activation of Nrf2/HO-1 Antioxidant Pathway by Heme Attenuates Calcification of Human Lens Epithelial Cells

Activation of Nrf2/HO-1 Antioxidant Pathway by Heme Attenuates Calcification of Human Lens Epithelial Cells

Cataract, an opacification in the crystalline lens, is a leading cause of blindness. Deposition of hydroxyapatite occurs in a cataractous lens that could be the consequence of osteogenic differentiation of lens epithelial cells (LECs). Nuclear factor erythroid 2-related factor 2 (Nrf2) controls the...

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Bibliographic Details
Main Authors:	Ababneh, H. (Author), Balogh, E. (Author), Chowdhury, A. (Author), Jeney, V. (Author), Tóth, A. (Author)
Format:	Article
Language:	English
Published:	MDPI 2022
Subjects:	cataract heme heme oxygenase-1 (HO-1) iron lens calcification lens epithelial cells nuclear factor erythroid 2-related factor 2 (Nrf2) osteogenic differentiation
Online Access:	View Fulltext in Publisher

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