Delayed pulmonary metastasis and recurrence of intracranial malignant solitary fibrous tumor/hemangiopericytoma: Case report and literature review

Solitary fibrous tumors/hemangiopericytomas (SFTs/HPCs) are intracranial spindle cell tumors that originate from interstitial tissue. SFTs/HPCs that are primary malignant intracranial tumors are exceedingly uncommon. A case of intracranial malignant SFT/HPC that originated intracrani‑ ally and sprea...

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Bibliographic Details
Main Authors: Li, Q. (Author), Li, Z. (Author), Zhang, C. (Author)
Format: Article
Language:English
Published: Spandidos Publications 2022
Subjects:
Online Access:View Fulltext in Publisher
LEADER 01856nam a2200205Ia 4500
001 10.3892-ol.2022.13375
008 220718s2022 CNT 000 0 und d
020 |a 17921074 (ISSN) 
245 1 0 |a Delayed pulmonary metastasis and recurrence of intracranial malignant solitary fibrous tumor/hemangiopericytoma: Case report and literature review 
260 0 |b Spandidos Publications  |c 2022 
856 |z View Fulltext in Publisher  |u https://doi.org/10.3892/ol.2022.13375 
520 3 |a Solitary fibrous tumors/hemangiopericytomas (SFTs/HPCs) are intracranial spindle cell tumors that originate from interstitial tissue. SFTs/HPCs that are primary malignant intracranial tumors are exceedingly uncommon. A case of intracranial malignant SFT/HPC that originated intracrani‑ ally and spread to the pulmonary region is described herein. Furthermore, the specimens from two surgical resections obtained when the patient had undergone two prior procedures for intracranial ‘meningiomas’ were also reviewed. The results of the lung biopsy matched the morphologic appearance of the intracranial tumor. The patient died ~2 years after the chest pain started. In addition, the literature was reviewed. According to previous studies, STAT6 expression was positive in 100% of SFTs/HPCs and radiologic characteristics assisted in deter‑ mining the tumor pathology and grade. Surgical management has been the mainstay treatment for SFTs. In cases of incom‑ plete resection, adjuvant radiotherapy is effective and rigorous follow‑up is required to monitor for recurrence. © 2022 Spandidos Publications. All rights reserved. 
650 0 4 |a hemangiopericytoma 
650 0 4 |a meningiomas 
650 0 4 |a primary brain tumors 
650 0 4 |a solitary fibrous tumors 
700 1 |a Li, Q.  |e author 
700 1 |a Li, Z.  |e author 
700 1 |a Zhang, C.  |e author 
773 |t Oncology Letters