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01856nam a2200205Ia 4500 |
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10.3892-ol.2022.13375 |
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|a 17921074 (ISSN)
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|a Delayed pulmonary metastasis and recurrence of intracranial malignant solitary fibrous tumor/hemangiopericytoma: Case report and literature review
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|b Spandidos Publications
|c 2022
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|z View Fulltext in Publisher
|u https://doi.org/10.3892/ol.2022.13375
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|a Solitary fibrous tumors/hemangiopericytomas (SFTs/HPCs) are intracranial spindle cell tumors that originate from interstitial tissue. SFTs/HPCs that are primary malignant intracranial tumors are exceedingly uncommon. A case of intracranial malignant SFT/HPC that originated intracrani‑ ally and spread to the pulmonary region is described herein. Furthermore, the specimens from two surgical resections obtained when the patient had undergone two prior procedures for intracranial ‘meningiomas’ were also reviewed. The results of the lung biopsy matched the morphologic appearance of the intracranial tumor. The patient died ~2 years after the chest pain started. In addition, the literature was reviewed. According to previous studies, STAT6 expression was positive in 100% of SFTs/HPCs and radiologic characteristics assisted in deter‑ mining the tumor pathology and grade. Surgical management has been the mainstay treatment for SFTs. In cases of incom‑ plete resection, adjuvant radiotherapy is effective and rigorous follow‑up is required to monitor for recurrence. © 2022 Spandidos Publications. All rights reserved.
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|a hemangiopericytoma
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|a meningiomas
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|a primary brain tumors
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|a solitary fibrous tumors
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|a Li, Q.
|e author
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|a Li, Z.
|e author
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|a Zhang, C.
|e author
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|t Oncology Letters
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