Synthesis, antibacterial and lipoxygenase inhibition studies of N-(Alkyl/aralkyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-methylbenzenesulfonamides

Synthesis, antibacterial and lipoxygenase inhibition studies of N-(Alkyl/aralkyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-methylbenzenesulfonamides

Objectives: The present research work was aimed to synthesize some new sulfonamides bearing 1,4-benzodioxin ring, which might have suitable antibacterial potential and can be used as possible therapeutic agents for inflammatory ailments. Materials and Methods: The synthesis was accomplished by the r...

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Bibliographic Details
Main Authors:	Abbasi, M.A (Author), Ahmad, I. (Author), Aziz-ur-rehman (Author), Malik, R. (Author), Nazir, S. (Author), Shah, S.A (Author), Sheeza, A. (Author), Siddiqui, S.Z (Author)
Format:	Article
Language:	English
Published:	Turkish Pharmacists Association 2017
Subjects:	1H-NMR 2 3-dihydro-1 4-benzodioxin-6-amine antibacterial activity Antibacterial potential antiinfective agent Article Bacillus subtilis ciprofloxacin controlled study drug determination drug effect drug structure drug synthesis enzyme inhibition Escherichia coli growth inhibition infrared radiation lipoxygenase Lipoxygenase mass spectrometry minimum inhibitory concentration n (2 bromoethyl) n (2,3 dihydro 1,4 benzodioxin 6 yl) 4 methylbenzenesulfonamide n (2 chlorobenzyl) n (2,3 dihydro 1,4 benzodioxin 6 yl) 4 methylbenzenesulfonamide n (2,3 dihydro 1,4 benzodioxin 6 yl) 4 methylbenzenesulfonamide n (2,3 dihydro 1,4 benzodioxin 6 yl) n (2 phenethyl) 4 methylbenzenesulfonamide n (2,3 dihydro 1,4 benzodioxin 6 yl) n (3 phenylpropyl) 4 methylbenzenesulfonamide n (4 chlorobenzyl) n (2,3 dihydro 1,4 benzodioxin 6 yl) 4 methylbenzenesulfonamide n (alkyl aralkyl) n (2,3 dihydro 1,4 benzodioxin 6 yl) 4 methylbenzenesulfonamide nonhuman proton nuclear magnetic resonance Salmonella enterica serovar Typhi unclassified drug
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