Central and systemic endotoxin challenges exacerbate the local inflammatory response and increase neuronal death during chronic neurodegeneration

The contribution of inflammation to the progression of eurodegenerative diseases such as Alzheimer's, Parkinson's, and prion diseases is poorly understood. Brain inflammation in animal models of these diseases is dominated by chronic microglial activation with minimal proinflammatory cytok...

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Bibliographic Details
Main Authors: Cunningham, Colm (Author), Wilcockson, David C. (Author), Campion, Suzanne (Author), Lunnon, Katie (Author), Perry, V. Hugh (Author)
Format: Article
Language:English
Published: 2005-10-05.
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