Double blind, randomised, placebo controlled study of a platelet activating factor antagonist, lexipafant, in the treatment and prevention of organ failure in predicted severe acute pancreatitis
Background: platelet activating factor (PAF) is believed to amplify the activity of key mediators of the systemic inflammatory response syndrome (SIRS) in acute pancreatitis, resulting in multiorgan dysfunction syndrome. We tested the hypothesis that a potent PAF antagonist, lexipafant, could dampen...
Main Authors: | Johnson, C.D (Author), Kingsnorth, A.N (Author), Imrie, C.W (Author), McMahon, M.J (Author), Neoptolemos, J.P (Author), McKay, C. (Author), Toh, S.K (Author), Skaife, P. (Author), Leeder, P.C (Author), Wilson, P. (Author), Larvin, M. (Author), Curtis, L.D (Author) |
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Format: | Article |
Language: | English |
Published: |
2001.
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Subjects: | |
Online Access: | Get fulltext |
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