T cell immunity to lymphoma following treatment with anti-CD40 monoclonal antibody

In this study we demonstrate that treatment with anti-CD40 mAb eradicates a range of mouse lymphomas (BCL1, A31, A20, and EL4), but only when used against i.v. tumor doses in excess of 107 cells. Only partial protection was seen against smaller tumor loads. We saw no evidence that anti-CD40 mAb chan...

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Bibliographic Details
Main Authors: Tutt, Alison L. (Author), O'Brien, Lyn (Author), Hussain, Akmal (Author), Crowther, Graham R. (Author), French, Ruth R. (Author), Glennie, Martin J. (Author)
Format: Article
Language:English
Published: 2002-03.
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