No evidence of an association between mitochondrial DNA variants and osteoarthritis in 7393 cases and 5122 controls

Objectives Osteoarthritis (OA) has a complex aetiology with a strong genetic component. Genome-wide association studies implicate several nuclear genes in the aetiology, but a major component of the heritability has yet to be defined at the molecular level. Initial studies implicate maternally inher...

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Main Authors: Hudson, G. (Author), Panoutsopoulou, K. (Author), Wilson, I. (Author), Southam, L. (Author), Rayner, N.W (Author), Arden, Nigel (Author), Birrell, F. (Author), Carluke, I. (Author), Carr, A. (Author), Chapman, K. (Author), Deloukas, P. (Author), Doherty, P. (Author), McCaskie, A. (Author), Ollier, W.E (Author), Ralston, S.H (Author), Reed, M.R (Author), Spector, T.D (Author), Valdes, A.M (Author), Wallis, G.A (Author), Wilkinson, J.M (Author), Zeggini, E. (Author), Samuels, D.C (Author), Loughlin, J. (Author), Chinnery, P.F (Author)
Format: Article
Language:English
Published: 2013-01.
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