Multiple congenital melanocytic nevi and neurocutaneous melanosis are caused by postzygotic mutations in codon 61 of NRAS

Multiple congenital melanocytic nevi and neurocutaneous melanosis are caused by postzygotic mutations in codon 61 of NRAS

Congenital melanocytic nevi (CMN) can be associated with neurological abnormalities and an increased risk of melanoma. Mutations in NRAS, BRAF, and Tp53 have been described in individual CMN samples; however, their role in the pathogenesis of multiple CMN within the same subject and development of a...

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Main Authors: Kinsler, Veronica A. (Author), Thomas, Anna C. (Author), Ishida, Miho (Author), Bulstrode, Neil W. (Author), Loughlin, Sam (Author), Hing, Sandra (Author), Chalker, Jane (Author), McKenzie, Kathryn (Author), Abu-Amero, Sayeda (Author), Slater, Olga (Author), Chanudet, Estelle (Author), Palmer, Rodger (Author), Morrogh, Deborah (Author), Stanier, Philip (Author), Healy, Eugene (Author), Sebire, Neil J. (Author), Moore, Gudrun E. (Author)
Format: Article
Language:English
Published: 2013-09.
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