Energy, ageing, fidelity and sex: oocyte mitochondrial DNA as a protected genetic template

Energy, ageing, fidelity and sex: oocyte mitochondrial DNA as a protected genetic template

Oxidative phosphorylation couples ATP synthesis to respiratory electron transport. In eukaryotes, this coupling occurs in mitochondria, which carry DNA. Respiratory electron transport in the presence of molecular oxygen generates free radicals, reactive oxygen species (ROS), which are mutagenic. In...

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Bibliographic Details
Main Authors: de Paula, Wilson B.M (Author), Lucas, Cathy H. (Author), Agip, Ahmed-Noor A. (Author), Vizcay-Barrena, Gema (Author), Allen, John F. (Author)
Format: Article
Language:English
Published: 2013-07-19.
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