Interaction of prenatal maternal smoking, interleukin 13 genetic variants and DNA methylation influencing airflow and airway reactivity

Background Asthma is characterized by airflow limitation and airway reactivity (AR). Interleukin-13 (IL-13) is involved in the pathogenesis of asthma. Two functional SNPs, rs20541 and rs1800925, of the IL-13 gene (IL13) have been frequently associated with asthma-related lung functions. However, ge...

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Main Authors: Patil, Veeresh K (Author), Holloway, John W (Author), Zhang, Hongmei (Author), Soto-Ramirez, Nelis (Author), Ewart, Susan (Author), Arshad, S Hasan (Author), Karmaus, Wilfried (Author)
Format: Article
Language:English
Published: 2013-12-06.
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