Autologous transfusion of stored red blood cells increases pulmonary artery pressure

Autologous transfusion of stored red blood cells increases pulmonary artery pressure

RATIONALE: Transfusion of erythrocytes stored for prolonged periods is associated with increased mortality. Erythrocytes undergo hemolysis during storage and after transfusion. Plasma hemoglobin scavenges endogenous nitric oxide leading to systemic and pulmonary vasoconstriction. OBJECTIVES: We hyp...

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Main Authors: Berra, Lorenzo (Author), Pinciroli, Riccardo (Author), Stowell, Christopher P. (Author), Wang, Lin (Author), Yu, Binglan (Author), Fernandez, Bernadette O. (Author), Feelisch, Martin (Author), Mietto, Cristina (Author), Hod, Eldad A. (Author), Chipman, Daniel (Author), Scherrer-Crosbie, Marielle (Author), Bloch, Kenneth D. (Author), Zapol, Warren M. (Author)
Format: Article
Language:English
Published: 2014-10-01.
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