Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer's-like pathology
The proliferation and activation of microglial cells is a hallmark of several neurodegenerative conditions. This mechanism is regulated by the activation of the colony-stimulating factor 1 receptor (CSF1R), thus providing a target that may prevent the progression of conditions such as Alzheimer'...
Main Authors: | Olmos-Alonso, A. (Author), Schetters, S.T.T (Author), Sri, S. (Author), Askew, K. (Author), Mancuso, R. (Author), Vargas-Caballero, M. (Author), Holscher, C. (Author), Perry, V.H (Author), Gomez-Nicola, D. (Author) |
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Format: | Article |
Language: | English |
Published: |
2016-03.
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Subjects: | |
Online Access: | Get fulltext |
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